How to Treat Alpha Thalassemia?
Alpha thalassemia is an anemic variant that occurs when there is the fault with the chain of Alpha-globin protein. A chain of 4 genes is needed to be there in order to make sure that the red blood cells are properly produced (2 from each pair). Based on the number of genes at fault, alpha thalassemia is divided into 4 variants:
- One gene fault: This is a benign fault and there are no anemic symptoms in the patient. However, because of biological magnification, the offspring of the person carrying this gene might show some anemic symptoms.
- Two gene fault: In case of the two gene fault, the person shows only slight anemic symptoms. It mostly because the red blood cells that are created is smaller than usual.
- Three gene Fault: If there is a fault with 75 percent of the genes that make up the alpha-globin protein, the symptoms of Hepatitis H starts to develop. Now, the symptoms of this condition can range from mild to severe.
- Four gene fault: When all the 4 genes are either mutated or missing, there is a case of alpha-thalassaemia major. In this condition, the fetus ends up dying.
Alpha Thalassemia treatment
The treatment of this particular variant of the thalassaemic condition involves the following:
- Occasional blood transfusions: Children that have this particular variant of the condition occasionally require blood transfusions. However, care is taken to make sure that the blood is of the matching type and the transfusion is not overdone to make sure that there is no iron overload.
- Iron Chelation: It is a post-transfusion treatment that is required in order to remove excess iron from the patients’ system. Iron Chelation is mostly done by giving certain medication to the patient’s that removes excess amount of iron from their system within a matter of hours.
- Bone marrow transplant: Bone marrow transplant or stem cell transplantation is one of the only viable known full cures of the condition. In this treatment, preserved bone marrow cells are transplanted into the system of the patient to ensure the reproduction of healthy red blood cells.
- Genetic Counselling: For the couples who have the mutated gene and are considering children, a genetic counseling is provided that educates them of all the risks and the things they can do to prevent the severe symptoms in their offspring.
If you want the best version of the above-mentioned treatments, you should confer with the experts of Fortis Hospital in Gurgaon. There, the three doctors in charge of the Hematologist department: Dr. Vikas Dua, Dr. Rahul Bhargava and Dr. Aniruddha Dayama will provide you with all the treatments that you require.