What are the complications Involved with Myelofibrosis?
Myelofibrosis is a type of blood disorder that causes damages to the red blood cell production of the bone marrow. Due to the nature of the disease, one can guess that most of its symptoms are anemic. It is also necessary to know that Myelofibrosis is a rate version of Leukaemia. To that end, if left untreated or the treated late, this complications involved with this disease can be quite severe.
Complications from Myelofibrosis
When it comes to Myelofibrosis, the initial symptoms tend to be benign or not any. However, there are always some things that eventually lead to complications. The most prevalent among them are as follows:
- Increase flow velocity of blood into the liver: When the blood arrives into the liver through the spleen, it does so by the portal vein. However, the bigger the spleen is, the more blood it produces. Consequently, the flow velocity in the portal vein increases and it can cause the rupture and eventual bleeding of the vein.
- Back Pain: If the spleen is enlarged to a severe extent, immense pain can be felt through the abdominal or back.
- Growth in other areas: as Myelofibrosis causes the production of blood cells outside the bone marrow, mini tumors of blood-producing regions can be created throughout the body. This further complicates and symptoms like gastrointestinal problems, coughing up blood, seizures and other symptoms become quite common.
- Easy bleeding: As the case of this disease become more severe, the platelet count in the body is severely affected. As a consequence, the body bleeds quite profusely and easily. This sort of complication can make it quite difficult for the doctors to operate on the patient.
- Bone pain: When a scar is developed in the bone marrow, its spongy nature is compromised. Consequently, a significant amount of bone marrow hardening occurs. This escalates into bone pain and inflammation of the connective tissue, causing pain in the joints.
- Acute leukemia chances: when it comes to blood disorders, due to the reason that they happen, a patient can get extra diseases as a complication factor of the previous one. Same is the case with Myelofibrosis. It can lead to acute leukemia (a disease which compared to the titular one, progresses at a more rapid pace).